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I saw a recent video about the errors of alphafold 3.

https://www.youtube.com/watch?v=E61wJXlENoE



That video is saying that AlphaFold isn't good at predicting how proteins bind to each other, but is actually pretty good at predicting the structure of the individual proteins. Which is exactly what you would expect, because AlphaFold wasn't designed to predict antibody/antigen bindings. That's what AlphaProteo is now trying to solve. Also, as the video points out at the end, AlphaFold is well aware that it's unable to do this task and is communicating that fact via its ultra low confidences in the accuracy of the positioning of the proteins relative to each other. So I am not really sure what this video is trying to prove.




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