40 years of development here, too .. my solution to the RSI problem, which I discovered in the 80's, is quite simple: change my keyboard and mouse setup regularly - simply don't use the same keyboard/mouse for longer than 6 months, maximum.

Adopting this policy has kept RSI problems at bay, at least in my case. I have 3 or 4 favourite keyboards and I just switch them around ... giving my hands a chance to re-train on different weights/resistances of keys, etc.