The best non-fiction book I read in 2022 was Plagues Upon the Earth (https://www.goodreads.com/book/show/57423807-plagues-upon-th...) a history of infectious disease in humans. It really changed my views on a lot of things, especially how recently many contagious diseases crossed over from animals.
The best fiction book I read in 2022 was Spinning Silver (https://www.goodreads.com/book/show/36896898-spinning-silver). A really awesome riff on Russian fairy tales.