On being interrupted, "It's difficult to describe. Something like a physical sensation."

This is extremely relatable. I'm pretty confident that this physical sensation is related to my (rather severely) limited working memory, which I have to carefully manage at maximum capacity and which is catastrophically overwhelmed by some interruptions. A token interruption ("hey, do you have a sec"?) Doesn't tend to cause the sensation, but an interruption that contains data ("I called Greg about the plan for Wednesday and he said that Susan said...") is psychologically painful and even enraging in an oddly visceral sort of way.